d
dihydrocodeine
Chemical compound
Also known as DF-118 · Dicogesic® · dihydrocodeine bitartrate · Drocode · Paracodeine® · Dihydrocodeine
- Formula
- C₁₈H₂₃NO₃
1
- C₁₈H₂₃NO₃
- Mass
- 301.168 Da
1
- 301.168 Da
Overview
Chemistry
All data
180 statements · 71% with external sources · numbers in brackets are citations
- Isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)O
1
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)O
- Canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(CC4)O
1
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(CC4)O
- Defined daily dose
- 0.15 g route of administration: oral administration
- Significant drug interaction
- pethidine side effect: depressed level of consciousness
- pethidine side effect: central respiratory depression
- tramadol side effect: depressed level of consciousness
- tramadol side effect: central respiratory depression
- buprenorphine side effect: depressed level of consciousness
- buprenorphine side effect: central respiratory depression
- tapentadol side effect: depressed level of consciousness
- tapentadol side effect: central respiratory depression
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- sufentanil side effect: depressed level of consciousness
- sufentanil side effect: central respiratory depression
- (RS)-methadone side effect: depressed level of consciousness
- (RS)-methadone side effect: central respiratory depression
- morphine side effect: depressed level of consciousness
- morphine side effect: central respiratory depression
- hydromorphone side effect: depressed level of consciousness
- hydromorphone side effect: central respiratory depression
- fentanyl side effect: depressed level of consciousness
- fentanyl side effect: central respiratory depression
- codeine side effect: depressed level of consciousness
- codeine side effect: central respiratory depression
- remifentanil side effect: depressed level of consciousness
- remifentanil side effect: central respiratory depression
- alfentanil side effect: depressed level of consciousness
- alfentanil side effect: central respiratory depression
- oxycodone side effect: depressed level of consciousness
- oxycodone side effect: central respiratory depression
- periciazine side effect: depressed level of consciousness
- (±)-promethazine side effect: depressed level of consciousness
- (±)-promethazine side effect: central respiratory depression
- levomepromazine side effect: depressed level of consciousness
- levomepromazine side effect: central respiratory depression
- trimeprazine side effect: depressed level of consciousness
- trimeprazine side effect: central respiratory depression
- nitrazepam side effect: depressed level of consciousness
- nitrazepam side effect: central respiratory depression
- zopiclone side effect: depressed level of consciousness
- zopiclone side effect: central respiratory depression
- clobazam side effect: depressed level of consciousness
- clobazam side effect: central respiratory depression
- dexmedetomidine side effect: depressed level of consciousness
- dexmedetomidine side effect: central respiratory depression
- (RS)-sulpiride side effect: depressed level of consciousness
- (RS)-sulpiride side effect: central respiratory depression
- perampanel side effect: depressed level of consciousness
- perampanel side effect: central respiratory depression
- (±)-thiopental side effect: depressed level of consciousness
- (±)-thiopental side effect: central respiratory depression
- midazolam side effect: depressed level of consciousness
- midazolam side effect: central respiratory depression
- (RS)-baclofen side effect: depressed level of consciousness
- (RS)-baclofen side effect: central respiratory depression
- diazepam side effect: depressed level of consciousness
- diazepam side effect: central respiratory depression
- oxazepam side effect: depressed level of consciousness
- oxazepam side effect: central respiratory depression
- droperidol side effect: depressed level of consciousness
- droperidol side effect: central respiratory depression
- zolpidem side effect: depressed level of consciousness
- zolpidem side effect: central respiratory depression
- pimozide side effect: depressed level of consciousness
- Substance control status
- Schedule II (Russia) applies to jurisdiction: Russia
1
Sources- 1.Stated in Government Decree No. 681 of 30 June 1998 (Russia)consultant.ru/document/cons_doc_LAW_19243/Retrieved 2026-08-31
- Schedule I (Canada) applies to jurisdiction: Canada
- Anlage III (Germany) applies to jurisdiction: Germany
- Class B (United Kingdom) applies to jurisdiction: United Kingdom
- Schedule II (United States) applies to jurisdiction: United States
- Schedule II (Russia) applies to jurisdiction: Russia
On other databases
31 identifiers linking dihydrocodeine across the web's reference databases
- ATC codeN02AA08
- CAS Registry Number125-28-0
- ChEBI ID135276
- ChEMBL IDCHEMBL1595
- ChemSpider ID4447600
- DrugBank IDDB01551
- DrugCentral ID886
- DSSTOX compound identifierDTXCID302936
- DSSTox substance IDDTXSID5022936
- EC number204-732-3
- ECHA Substance Infocard ID100.004.303
- Freebase ID/m/03ys9h
- Guide to Pharmacology Ligand ID7594
- InChIInChI=1S/C18H23NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-13,17,20H,4-5,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
- InChIKeyRBOXVHNMENFORY-DNJOTXNNSA-N
- KBpedia IDDihydrocodeine
- KEGG IDD01481
- MassBank accession IDMSBNK-Athens_Univ-AU217801
- MeSH descriptor IDC014481
- Microsoft Academic ID (discontinued)2780708385
- NDF-RT IDN0000147812
- NSC number231319
- Probes And Drugs IDPD009479
- PubChem CID5284543
- Römpp online IDRD-04-01522
- RxNorm CUI23088
- SPLASHsplash10-0udi-0009000000-215351ab6e3d6923cb7a
- SureChEMBL ID24607
- UMLS CUIC0058056
- UniChem compound ID474105
- UNIIN9I9HDB855