m
morphine
Chemical compound
Also known as (-)-morphine · (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol · Morphia · morphium · (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol · (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
- Formula
- C₁₇H₁₉NO₃
1
- C₁₇H₁₉NO₃
- Mass
- 285.136 Da
1
- 285.136 Da
- Melting point
- 254°C
Overview
Chemistry
All data
327 statements · 60% with external sources · numbers in brackets are citations
- Medical condition treated
- pain
1
- dyspnea
1
- fibromyalgia
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- pain
- Canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
1
- CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
- Isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
1
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
- Discovered
- 1804
- Active ingredient in
- Avinza
1
- Infumorph
1
- Kadian
1
- Morphabond
1
- MS Contin
1
- Duramorph
1
- Astramorph
1
- Arymo
1
- Avinza
- Physically interacts with
- Opioid receptor delta 1 subject has role: agonist
1
- opioid receptor kappa 1 subject has role: agonist
1
- opioid receptor mu 1 subject has role: agonist
1
- Opioid receptor delta 1 subject has role: agonist
- Part of
- morphine receptor activity subject has role: reactant
1
- response to morphine subject has role: reactant
1
- morphine metabolic process subject has role: participant
1
- morphine catabolic process subject has role: reactant
1
- cellular response to morphine subject has role: reactant
1
- morphine biosynthetic process subject has role: product
1
- morphine receptor activity subject has role: reactant
- Found in taxon
- Papaver acrochaetum
- Papaver cylindricum
- Papaver gracile
- Papaver persicum
- Papaver setigerum
- Papaver commutatum
- Mytilus edulis
- Papaver bracteatum
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- Papaver rhoeas
- Papaver somniferum
40
Sources- 1.Stated in Radioimmunoassay determination of six opium alkaloids and its application to plant screening
- 2.Stated in Papaver somniferum L. var. album D.C. cultivated in Sicily: phytochemical investigation and use.
- 3.Stated in Morphine and codeine in poppy seed
- 4.Stated in Poppy Seed Ingestion as a Contributing Factor to Opiate-Positive Urinalysis Results: The Pacific Perspective
- 5.Stated in Poppy Seeds: Implications of Consumption
- 6.Stated in Gas chromatographic/mass spectrometric detection of narcotine, papaverine, and thebaine in seeds of Papaver somniferum
- Papaver arenarium
- Physalis angulata
- Papaver armeniacum
- Defined daily dose
- 30 milligram route of administration: parenteral route of administration
- 30 milligram route of administration: rectal route of administration
- Significant drug interaction
- pethidine side effect: depressed level of consciousness
- pethidine side effect: central respiratory depression
- tramadol side effect: depressed level of consciousness
- tramadol side effect: central respiratory depression
- buprenorphine side effect: depressed level of consciousness
- buprenorphine side effect: central respiratory depression
- tapentadol side effect: depressed level of consciousness
- tapentadol side effect: central respiratory depression
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- sufentanil side effect: depressed level of consciousness
- sufentanil side effect: central respiratory depression
- (RS)-methadone side effect: depressed level of consciousness
- (RS)-methadone side effect: central respiratory depression
- oxycodone side effect: depressed level of consciousness
- oxycodone side effect: central respiratory depression
- hydromorphone side effect: depressed level of consciousness
- hydromorphone side effect: central respiratory depression
- fentanyl side effect: depressed level of consciousness
- fentanyl side effect: central respiratory depression
- dihydrocodeine side effect: depressed level of consciousness
- dihydrocodeine side effect: central respiratory depression
- codeine side effect: depressed level of consciousness
- codeine side effect: central respiratory depression
- remifentanil side effect: depressed level of consciousness
- remifentanil side effect: central respiratory depression
- alfentanil side effect: depressed level of consciousness
- alfentanil side effect: central respiratory depression
- periciazine side effect: depressed level of consciousness
- (±)-promethazine side effect: paralytic ileus
- (±)-promethazine side effect: depressed level of consciousness
- (±)-promethazine side effect: central respiratory depression
- pimozide side effect: paralytic ileus
- pimozide side effect: depressed level of consciousness
- pimozide side effect: central respiratory depression
- fluphenazine side effect: paralytic ileus
- fluphenazine side effect: depressed level of consciousness
- fluphenazine side effect: central respiratory depression
- (RS)-hydroxyzine side effect: paralytic ileus
- (RS)-hydroxyzine side effect: depressed level of consciousness
- (RS)-hydroxyzine side effect: central respiratory depression
- olanzapine side effect: paralytic ileus
- olanzapine side effect: depressed level of consciousness
- olanzapine side effect: central respiratory depression
- loxapine side effect: paralytic ileus
- loxapine side effect: depressed level of consciousness
- loxapine side effect: central respiratory depression
- chlorpromazine side effect: paralytic ileus
- chlorpromazine side effect: depressed level of consciousness
- chlorpromazine side effect: central respiratory depression
- clozapine side effect: paralytic ileus
- clozapine side effect: depressed level of consciousness
- clozapine side effect: central respiratory depression
- chlorpheniramine side effect: paralytic ileus
- levomepromazine side effect: depressed level of consciousness
- levomepromazine side effect: central respiratory depression
- trimeprazine side effect: depressed level of consciousness
- trimeprazine side effect: central respiratory depression
- nitrazepam side effect: depressed level of consciousness
- nitrazepam side effect: central respiratory depression
- zopiclone side effect: depressed level of consciousness
- zopiclone side effect: central respiratory depression
- Substance control status
- Schedule II (Russia) applies to jurisdiction: Russia
1
Sources- 1.Stated in Government Decree No. 681 of 30 June 1998 (Russia)consultant.ru/document/cons_doc_LAW_19243/Retrieved 2026-08-31
- Schedule 8 (Australia) applies to jurisdiction: Australia
- Schedule I (Canada) applies to jurisdiction: Canada
- Anlage III (Germany) applies to jurisdiction: Germany
- Schedule II (United States) applies to jurisdiction: United States
- Schedule I (Single Convention 1961)
- Schedule III (Single Convention 1961)
- Schedule II (Russia) applies to jurisdiction: Russia
On other databases
75 identifiers linking morphine across the web's reference databases
- ATC codeN02AA01
- BBC Things ID42b10f8e-d912-4e38-8b53-55c12abf84f4
- Bibliothèque nationale de France ID11979266z
- BNCF Thesaurus ID22315
- CAS Registry Number57-27-2
- ChEBI ID17303
- ChEMBL IDCHEMBL70
- ChemSpider ID4450907
- Cultureel Woordenboek IDlevenswetenschappen-en-geneeskunde/morfine
- Dewey Decimal Classification362.293
- DrugBank IDDB00295
- DrugCentral ID1845
- DSSTOX compound identifierDTXCID203336
- DSSTox substance IDDTXSID9023336
- EC number200-320-2
- ECHA Substance Infocard ID100.000.291
- Electronic Essential Medicines List medicine ID12
- Encyclopædia Britannica Online IDscience/morphine
- Encyclopædia Universalis IDmorphine
- Encyclopedia of China (Third Edition) ID (2026)1OBX2W
- Encyclopedia of China (Third Edition) old ID (2021)141538
- FAST ID1026429
- Freebase ID/m/055pr
- GND ID4040284-8
- Great Russian Encyclopedia Online ID (2017)2231981
- Guide to Pharmacology Ligand ID1627
- HSDB ID2134
- Human Metabolome Database IDHMDB0014440
- IEDB Epitope ID116646
- IMDb keywordmorphine
- InChIInChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
- InChIKeyBQJCRHHNABKAKU-KBQPJGBKSA-N
- J9U entity ID987007546060405171
- JSTOR topic ID (archived)morphine
- KBpedia IDMorphine
- KEGG IDD08233
- KNApSAcK IDC00001889
- Lex IDmorfin
- Library of Congress Authorities IDsh85087342
- MassBank accession IDMSBNK-Athens_Univ-AU158001
- MedlinePlus drug identifiera682133
- MeSH descriptor IDD009020
- MeSH tree codeD03.132.577.249.562.571
- Microsoft Academic ID (discontinued)2777389121
- NALT ID8457
- NDF-RT IDN0000145914
- NDL Authority ID01035412
- NL CR AUT IDph187954
- Online PWN Encyclopedia ID3943467
- OpenAlex IDC2777389121
- PatientsLikeMe treatment IDmorphine
- PDB ligand IDMOI
- PDB structure ID1Q0Y
- Probes And Drugs IDPD010118
- PubChem CID5288826
- Quora topic IDMorphine
- Reaxys registry number93704
- RxNorm CUI7052
- ScienceDirect topic IDpharmacology-toxicology-and-pharmaceutical-science/morphine
- SPLASHsplash10-000i-0090000000-e9f7be236d827a716c1b
- Store medisinske leksikon IDmorfin
- SureChEMBL ID2997
- Treccani IDmorfina
- U.S. National Archives Identifier10641846
- UK Parliament thesaurus ID453858
- UMLS CUIC0026549
- UniChem compound ID136992
- UNII76I7G6D29C
- Vikidia article IDfr:Morphine
- WikiKids IDMorfine
- WikiProjectMed IDMorphine
- WikiSkripta article ID50792
- WordNet 3.1 Synset ID03791950-n
- Yale LUX IDconcept/8ae62c6c-befb-41c1-b9a6-7884d6e88512
- YSO ID10467