Human proteins (UniProt Swiss-Prot)
Every manually reviewed human protein in UniProtKB/Swiss-Prot, with its gene, recommended name, length, molecular mass, chromosome, cellular location, linked diseases and number of known 3D structures. One row per protein entry (canonical sequence).
Columns
Stable keys — use them in the API, SQL and code
| Key | Name | Type | Description |
|---|---|---|---|
| accession | UniProt | string | UniProt primary accession, e.g. P04637. |
| entry_name | Entry name | string | UniProt entry name, e.g. P53_HUMAN. |
| gene | Gene | string | Primary gene name (usually the HGNC symbol). |
| protein_name | Protein | string | UniProt recommended protein name. |
| length | Length | integer · aa | Number of amino acids in the canonical sequence. |
| mass_kda | Mass | number · kDa | Molecular mass of the canonical sequence in kilodaltons (UniProt gives daltons; 1 kDa = 1,000 Da). |
| chromosome | Chromosome | string | Chromosome of the encoding gene (1–22, X, Y, or MT for mitochondrial DNA). |
| ec_numbers | EC number | string | Enzyme Commission number(s) for enzymes. |
| locations | Location | string | Top-level subcellular locations, e.g. Nucleus; Cytoplasm; Cell membrane; Secreted. |
| transmembrane_helices | Transmembrane helices | integer | Number of transmembrane regions annotated. |
| disease_count | Diseases | integer | Number of diseases UniProt links to variants of this protein. |
| diseases | Disease names | string | Names of those diseases. |
| pdb_structures | 3D structures | integer | Number of experimentally determined 3D structures in the Protein Data Bank (PDB). |
| evidence_level | Evidence level | integer | UniProt protein-existence level: 1 evidence at protein level, 2 at transcript level, 3 inferred from homology, 4 predicted, 5 uncertain. |
| annotation_score | Annotation score | integer | UniProt annotation score, 1 (basic) to 5 (best annotated). |
| first_public | In UniProt since | date | Date the entry was first made public. |
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