r
rizatriptan
Chemical compound
Also known as MK-0462 · MK-462 · MK-A462 · N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine · risatriptan · N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine
- Formula
- C₁₅H₁₉N₅
1
- C₁₅H₁₉N₅
- Mass
- 269.164 Da
1
- 269.164 Da
Overview
Chemistry
All data
65 statements · 78% with external sources · numbers in brackets are citations
- Significant drug interaction
- isocarboxazid
- phenelzine
- tranylcypromine
- ergotamine side effect: vasoconstriction
- vortioxetine side effect: geniospasm
- vortioxetine side effect: mental status change
- vortioxetine side effect: hyperthermia
- vortioxetine side effect: hypertension
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- linezolid side effect: mental status change
- linezolid side effect: geniospasm
- linezolid side effect: hyperthermia
- linezolid side effect: hypertension
- phenelzine side effect: mental status change
- phenelzine side effect: hypertension
- phenelzine side effect: hyperthermia
- phenelzine side effect: geniospasm
- Canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
1
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
- Defined daily dose
- 10 milligram route of administration: oral administration
- Subject has role
- serotonin receptor agonists
2
Sources- 1.Stated in NDF-RTRetrieved 2018-03-05
- 2.Stated in Medical Subject HeadingsRetrieved 2018-03-15
- serotonin receptor agonists
- Medical condition treated
- migraine
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- migraine
- Physically interacts with
- 5-hydroxytryptamine receptor 1A subject has role: agonist
1
- 5-hydroxytryptamine receptor 1B subject has role: agonist
2
Sources- 1.Stated in IUPHAR/BPS Guide to PHARMACOLOGYRetrieved 2016-08-17
- 2.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL905Retrieved 2023-08-14
- 5-hydroxytryptamine receptor 1D subject has role: agonist
2
Sources- 1.Stated in IUPHAR/BPS Guide to PHARMACOLOGYRetrieved 2016-08-17
- 2.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL905Retrieved 2023-08-14
- 5-hydroxytryptamine receptor 1E subject has role: agonist
1
- 5-hydroxytryptamine receptor 1F subject has role: agonist
1
- 5-hydroxytryptamine receptor 1A subject has role: agonist
On other databases
32 identifiers linking rizatriptan across the web's reference databases
- ATC codeN02CC04
- CAS Registry Number144034-80-0
- ChEBI ID48273
- ChEMBL IDCHEMBL905
- ChemSpider ID4900
- DrugBank IDDB00953
- DrugCentral ID2393
- DSSTOX compound identifierDTXCID103565
- DSSTox substance IDDTXSID2023565
- EC number812-626-9
- ECHA Substance Infocard ID100.243.719
- Freebase ID/m/03p1n8
- Guide to Pharmacology Ligand ID51
- Human Metabolome Database IDHMDB0015088
- InChIInChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3
- InChIKeyULFRLSNUDGIQQP-UHFFFAOYSA-N
- KEGG IDD00675
- MedlinePlus drug identifiera601109
- MeSH descriptor IDC093622
- Microsoft Academic ID (discontinued)2777030092
- NDF-RT IDN0000148576
- OpenAlex IDC2777030092
- PatientsLikeMe treatment IDrizatriptan
- Probes And Drugs IDPD009621
- PubChem CID5078
- Reaxys registry number7078976
- RxNorm CUI88014
- SureChEMBL ID26662
- UMLS CUIC0297635
- UniChem compound ID159800
- UNII51086HBW8G
- WikiProjectMed IDRizatriptan