p
pentoxifylline
Chemical compound
Also known as BL-191 · Trental® · Pentoxifyllin · Pentoxifyllinum · Pentoxifylline · Oxpentifylline
- Formula
- C₁₃H₁₈N₄O₃
1
- C₁₃H₁₈N₄O₃
- Mass
- 278.138 Da
1
- 278.138 Da
Overview
Chemistry
All data
88 statements · 67% with external sources · numbers in brackets are citations
- Medical condition treated
- diabetic angiopathy
1
- intermittent claudication
1
- diabetic polyneuropathy
1
- cerebral malaria
1
- arteriosclerosis
1
- brain ischemia
1
- silent stroke
1
- vasculogenic impotence
1
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- vasculitis
1
- cerebrovascular disease
1
- peripheral vascular disease
1
- intermittent claudication(since 1999) approved by: United States Food and Drug Administration
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/SD6QCT3TSURetrieved 2018-11-02
- diabetic angiopathy
- Canonical SMILES
- CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
1
- CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
- Half-life
- 0.6 h
- Physically interacts with
- Adenosine A2b receptor subject has role: antagonist
1
- Adenosine A2b receptor subject has role: antagonist
- Stylized name
- TRENtal has characteristic: Tall Man lettering · issued by: Institute for Safe Medication Practices
1
Sources- 1.ismp.org/recommendations/tall-man-letters-listRetrieved 2022-09-02
- TRENtal has characteristic: Tall Man lettering · issued by: Institute for Safe Medication Practices
- Significant drug interaction
- aminophylline side effect: seizure
- aminophylline side effect: nausea
- aminophylline side effect: vomiting
- aminophylline side effect: palpitation
- theophylline monohydrate side effect: seizure
- theophylline monohydrate side effect: nausea
- theophylline monohydrate side effect: vomiting
- theophylline monohydrate side effect: palpitation
On other databases
39 identifiers linking pentoxifylline across the web's reference databases
- ATC codeC04AD03
- CAB ID33911
- CAS Registry Number6493-05-6
- ChEBI ID7986
- ChEMBL IDCHEMBL628
- ChemSpider ID4578
- DrugBank IDDB00806
- DrugCentral ID2099
- DSSTOX compound identifierDTXCID803437
- DSSTox substance IDDTXSID7023437
- EC number229-374-5
- ECHA Substance Infocard ID100.026.704
- Freebase ID/m/06p91_
- Guide to Pharmacology Ligand ID7095
- Human Metabolome Database IDHMDB0014944
- InChIInChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8H,4-7H2,1-3H3
- InChIKeyBYPFEZZEUUWMEJ-UHFFFAOYSA-N
- KEGG IDC07424
- MassBank accession IDSM861402
- MedlinePlus drug identifiera685027
- MeSH concept IDM0016198
- MeSH descriptor IDD010431
- MeSH tree codeD03.633.100.759.758.824.651.700
- Microsoft Academic ID (discontinued)2780404050
- NDF-RT IDN0000146791
- NSC number758481
- OpenAlex IDC2780404050
- PDB ligand IDPNX
- PDB structure ID3TVX
- Probes And Drugs IDPD000975
- PubChem CID4740
- RxNorm CUI8013
- SPLASHsplash10-0059-2970000000-95d1edcd63b61b13b22e
- SureChEMBL ID34039
- UMLS CUIC0030899
- UniChem compound ID630243
- UNIISD6QCT3TSU
- WikiProjectMed IDPentoxifylline
- WordNet 3.1 Synset ID03919556-n