n
nitroglycerin
Chemical compound
Also known as glyceryl trinitrate · trinitroglycerin · nitroglycerine · trinitroglycerol · nitroglycerol · glycerol, nitric acid triester
- Formula
- C₃H₅N₃O₉
1
- C₃H₅N₃O₉
- Mass
- 227.003 Da
1
- 227.003 Da
- Melting point
- 56°F
- , 13°C
- Density
- 1.6 g/cm³
- Solubility
- 0.1 gram per 100 gram of solvent
Chemistry
All data
138 statements · 52% with external sources · numbers in brackets are citations
- Immediately dangerous to life or health
- 75 milligram per cubic metre
- Vapor pressure
- 0.0003 millimetre of mercury temperature: 68°F
- Ceiling exposure limit
- 2 milligram per cubic metre applies to jurisdiction: United States
- Short-term exposure limit
- 0.1 milligram per cubic metre applies to jurisdiction: none · runtime: 15 min · route of administration: skin absorption
- World Health Organisation international non-proprietary name
- glyceryl trinitrate
1
- glyceryl trinitrate
- Canonical SMILES
- C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
1
- C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
- Discovered
- 1847
- Active ingredient in
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- Safety classification and labelling
- NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response nfpa health: 2 · nfpa fire: 2 · nfpa instability: 4
- Part of
- nitroglycerin metabolic process subject has role: participant
1
- response to nitroglycerin subject has role: reactant
1
- cellular response to nitroglycerin subject has role: reactant
1
- nitroglycerin metabolic process subject has role: participant
- Defined daily dose
- 5 milligram route of administration: oral administration
- Physically interacts with
- Guanylate cyclase 1 soluble subunit alpha 2 subject has role: activation
1
Sources- 1.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL730Retrieved 2023-08-14
- Guanylate cyclase 1 soluble subunit beta 1 subject has role: activation
1
Sources- 1.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL730Retrieved 2023-08-14
- Guanylate cyclase 1 soluble subunit alpha 2 subject has role: activation
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
- Significant drug interaction
- riociguat side effect: hypotension
- vardenafil side effect: hypotension
- sildenafil side effect: hypotension
- tadalafil side effect: hypotension
- avanafil side effect: hypotension
On other databases
67 identifiers linking nitroglycerin across the web's reference databases
- Art & Architecture Thesaurus ID300015122
- ATC codeC05AE01
- Bibliothèque nationale de France ID11968823w
- BNCF Thesaurus ID37660
- CAMEO Chemicals ID1531
- CAS Registry Number55-63-0
- ChEBI ID28787
- ChEMBL IDCHEMBL730
- ChemSpider ID4354
- Dewey Decimal Classification662.27
- DrugBank IDDB00727
- DrugCentral ID1952
- DSSTOX compound identifierDTXCID701407
- DSSTox substance IDDTXSID1021407
- EC number200-240-8
- ECHA Substance Infocard ID100.000.219
- Encyclopædia Britannica Online IDscience/nitroglycerin
- Encyclopedia of China (Second Edition) ID239149
- Encyclopedia of China (Third Edition) ID (2026)4UDXuR
- Encyclopedia of China (Third Edition) old ID (2021)156998
- Freebase ID/m/05dkv
- Gmelin number165859
- GND ID4042391-8
- Great Norwegian Encyclopedia IDnitroglyserin_-_sprengstoff
- Great Russian Encyclopedia portal IDnitroglitserin-7ecac9
- Guide to Pharmacology Ligand ID7053
- HCIS ID2330
- HSDB ID30
- Human Metabolome Database IDHMDB0014865
- ICSC ID0186
- InChIInChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
- InChIKeySNIOPGDIGTZGOP-UHFFFAOYSA-N
- J9U entity ID987007531390805171
- KBpedia IDNitroglycerine
- KEGG IDD00515
- Lex IDnitroglycerin
- Library of Congress Authorities IDsh85092085
- MedlinePlus drug identifiera601086
- MeSH descriptor IDD005996
- MeSH tree codeD02.640.636
- Museum-digital tag ID45157
- Namuwiki ID니트로글리세린
- NDF-RT IDN0000145909
- NDL Authority ID00568571
- NicoNicoPedia word article IDニトログリセリン
- OSHA Occupational Chemical Database ID406
- PDB ligand IDTNG
- PDB structure ID4FR8
- Pixiv Encyclopedia IDニトログリセリン
- Probes And Drugs IDPD000256
- PubChem CID4510
- Quora topic IDNitroglycerin
- Reaxys registry number1802063
- RTECS numberQX2100000
- RxNorm CUI4917
- ScienceDirect topic IDphysics-and-astronomy/nitroglycerin
- SureChEMBL ID15421
- UM-BBD compound IDc0061
- UMLS CUIC0017887
- UN number0143
- UniChem compound ID540903
- UNIIG59M7S0WS3
- Vikidia article IDfr:Nitroglycérine
- WikiProjectMed IDNitroglycerin
- WordNet 3.1 Synset ID14910730-n
- Yale LUX IDconcept/1ce41a6a-0ef8-4a87-99b2-e1c7e3a17956
- ZVG number41320