n
nefazodone
Chemical compound
Also known as BMY-13754 · MJ-13754-1 · 1-{3-[4-(m-chlorophenyl)-1-piperazinyl]propyl}-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one
- Formula
- C₂₅H₃₂ClN₅O₂
1
- C₂₅H₃₂ClN₅O₂
- Mass
- 469.224 Da
1
- 469.224 Da
Overview
Chemistry
All data
61 statements · 75% with external sources · numbers in brackets are citations
- Medical condition treated
- neurotic disorder
1
- post-traumatic stress disorder
1
- depression(since 2003) approved by: United States Food and Drug Administration
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/59H4FCV1TFRetrieved 2018-11-02
- neurotic disorder
- Canonical SMILES
- CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl
1
- CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl
- Defined daily dose
- 0.4 g route of administration: oral administration
- Physically interacts with
- 5-hydroxytryptamine receptor 2A subject has role: antagonist
1
- cytochrome P450 family 3 subfamily A member 4 subject has role: antagonist
1
- Solute carrier family 6 member 2 subject has role: antagonist
1
- solute carrier family 6 member 4 subject has role: antagonist
1
- 5-hydroxytryptamine receptor 2A subject has role: antagonist
On other databases
36 identifiers linking nefazodone across the web's reference databases
- ATC codeN06AX06
- CAS Registry Number83366-66-9
- ChEBI ID7494
- ChEMBL IDCHEMBL623
- ChemSpider ID4294
- DrugBank IDDB01149
- DrugCentral ID1890
- DSSTOX compound identifierDTXCID203357
- DSSTox substance IDDTXSID2023357
- Encyclopædia Britannica Online IDtopic/nefazodone
- Freebase ID/m/077xgw
- Guide to Pharmacology Ligand ID7247
- HSDB ID8411
- Human Metabolome Database IDHMDB0015280
- InChIInChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3
- InChIKeyVRBKIVRKKCLPHA-UHFFFAOYSA-N
- Interlingual Index IDi56553
- KBpedia IDNefazodone
- KEGG IDC07256
- MedlinePlus drug identifiera695005
- MeSH descriptor IDC051752
- Microsoft Academic ID (discontinued)2779419675
- NDF-RT IDN0000148387
- OpenAlex IDC2779419675
- Probes And Drugs IDPD001694
- PubChem CID4449
- Reaxys registry number4728403
- Römpp online IDRD-14-00677
- RxNorm CUI31565
- SPLASHsplash10-0uk9-9846000000-49cb6e97c09a9e806dd5
- SureChEMBL ID35089
- UMLS CUIC0068485
- UniChem compound ID351065
- UNII59H4FCV1TF
- WikiProjectMed IDNefazodone
- WordNet 3.1 Synset ID03822602-n