m
melphalan
Chemical compound
Also known as MLP673 · Alkeran® · CB-3025 · L-phenylalanine mustard (L-PAM) · L-sarcolysine · melfalan
- Formula
- C₁₃H₁₈Cl₂N₂O₂
1
- C₁₃H₁₈Cl₂N₂O₂
- Mass
- 304.0745 Da
1
- 304.0745 Da
Overview
Chemistry
All data
74 statements · 66% with external sources · numbers in brackets are citations
- Medical condition treated
- multiple myeloma
1
- breast cancer
1
- ovarian cancer
1
- rhabdomyosarcoma
1
- neuroblastoma
1
- amyloidosis
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- neuroblastoma, susceptibility to
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- multiple myeloma
- Canonical SMILES
- C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl
1
- C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl
- Isomeric SMILES
- C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl
1
- C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl
- Subject has role
- alkylating agent
1
- alkylating antineoplastic agent
1
- myeloablative agonists
1
- developmental toxicant(since 1990)
1
Sources- 1.Stated in California Proposition 65 list of chemicalsoehha.ca.gov/chemicals/melphalanRetrieved 2020-03-18
- carcinogen
1
Sources- 1.Stated in California Proposition 65 list of chemicalsoehha.ca.gov/chemicals/melphalanRetrieved 2020-03-18
- alkylating agent
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
On other databases
46 identifiers linking melphalan across the web's reference databases
- ATC codeL01AA03
- CA PROP 65 IDmelphalan
- CAMEO Chemicals ID16224
- CAS Registry Number148-82-3
- ChEBI ID28876
- ChEMBL IDCHEMBL852
- ChemSpider ID405297
- DeCS ID8727
- DrugBank IDDB01042
- DrugCentral ID1678
- DSSTOX compound identifierDTXCID00804
- DSSTox substance IDDTXSID6020804
- EC number205-726-3
- ECHA Substance Infocard ID100.005.207
- Electronic Essential Medicines List medicine ID556
- Freebase ID/m/07d6lp
- Guide to Pharmacology Ligand ID7620
- HSDB ID3234
- Human Metabolome Database IDHMDB0015176
- IEDB Epitope ID141802
- InChIInChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1
- InChIKeySGDBTWWWUNNDEQ-LBPRGKRZSA-N
- Interlingual Index IDi56129
- KEGG IDD00369
- MedlinePlus drug identifiera682220
- MeSH concept IDM0013330
- MeSH descriptor IDD008558
- MeSH tree codeD02.455.526.728.650.594
- Microsoft Academic ID (discontinued)2778684742
- NDF-RT IDN0000147066
- NSC number241286
- OpenAlex IDC2778684742
- PatientsLikeMe treatment IDmelphalan
- PDB ligand IDVUC
- Probes And Drugs IDPD001871
- PubChem CID460612
- Reaxys registry number2816456
- RxNorm CUI6718
- Store medisinske leksikon IDmelfalan
- SureChEMBL ID5872
- UMLS CUIC0025241
- UNIIQ41OR9510P
- Wellcome Collection concept IDd6cp66c8
- WikiProjectMed IDMelphalan
- WordNet 3.1 Synset ID03749068-n
- World Health Organisation international non-proprietary name numeric ID745