m
melatonin
Hormone primarily released by the pineal gland
Also known as MLT · N-[2-(5-methoxyindol-3-yl)ethyl]acetamide · 5-methoxy-N-acetyltryptamine · Melovine · {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide · N-(2-(5-Methoxyindol-3-yl)ethyl)-Acetamide
- Formula
- C₁₃H₁₆N₂O₂
1
- C₁₃H₁₆N₂O₂
- Mass
- 232.121 Da
1
- 232.121 Da
Overview
Chemistry
All data
257 statements · 58% with external sources · numbers in brackets are citations
- Canonical SMILES
- CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
1
- CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
- Isomeric SMILES
- C/C(=N\CCC1=CNC2=C1C=C(C=C2)OC)/O
1
- C/C(=N\CCC1=CNC2=C1C=C(C=C2)OC)/O
- Found in taxon
- Homo sapiens
3
Sources- 1.Stated in Recon 2.2: from reconstruction to model of human metabolism
- 2.Stated in Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles
- 3.Stated in A community-driven global reconstruction of human metabolism.
- Mesocricetus auratus
- Solanum pimpinellifolium
- potato
- Nicotiana tabacum
- Andrographis paniculata
1
- Angelica biserrata
1
- Angelica sinensis
1
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- Arnebia euchroma
1
- Artemisia annua
1
- Bombyx
1
- Chenopodium rubrum
- Cistanche deserticola
1
- Citrus reticulata
1
- Coptis chinensis
1
- Cornus officinalis
1
- Curcuma aeruginosa
1
- Chrysanthemum morifolium
1
- Desmodium styracifolium
1
- Eucommia ulmoides
1
- Gardenia jasminoides
1
- Schlegel's Japanese gecko
1
- Gentiana macrophylla
1
- Gentiana scabra
1
- Hypericum perforatum
- Ipomoea nil
1
- Leonurus japonicus
1
- Lobelia chinensis
1
- Lycium barbarum
1
- Mahonia bealei
1
- cabbage moth
- Morus alba
1
- Ophiopogon japonicus
1
- Panax pseudoginseng
1
- Phellodendron amurense
1
- Polygala tenuifolia
1
- Polygonatum sibiricum
1
- Wolfiporia cocos
1
- Prunus cerasus
- Pueraria montana var. lobata
1
- Pyrola decorata
1
- Rehmannia glutinosa
1
- Rheum palmatum
1
- Rubus chingii
1
- Saposhnikovia divaricata
1
- Schisandra chinensis
1
- Scolopendra subspinipes
1
- Scrophularia ningpoensis
1
- Scutellaria amoena
1
- Scutellaria baicalensis
1
- Scutellaria lateriflora
1
- Sophora flavescens
1
- clove
1
- Tanacetum parthenium
1
- Taxillus chinensis
1
- Uncaria rhynchophylla
1
- Viola philippica
1
- Macrohyporia cocos
1
- Epimedium brevicornu
1
- Citrus × deliciosa
1
- Homo sapiens
- Defined daily dose
- 2 milligram route of administration: oral administration
- Physically interacts with
- 5-hydroxytryptamine receptor 2B subject has role: antagonist
1
- Melatonin receptor 1A subject has role: antagonist
1
- Melatonin receptor 1B subject has role: antagonist
1
- Melatonin receptor 1B subject has role: agonist
1
Sources- 1.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL45Retrieved 2023-08-14
- Melatonin receptor 1A subject has role: agonist
1
Sources- 1.Stated in Open Targets Platformplatform.opentargets.org/drug/CHEMBL45Retrieved 2023-08-14
- 5-hydroxytryptamine receptor 2B subject has role: antagonist
- Part of
- melatonin receptor activity subject has role: reactant
1
- melatonin binding subject has role: reactant
1
- melatonin biosynthetic process subject has role: product
1
- melatonin metabolic process subject has role: participant
1
- melatonin catabolic process subject has role: reactant
1
- acetylserotonin O-methyltransferase activity
1
- melatonin receptor activity subject has role: reactant
On other databases
73 identifiers linking melatonin across the web's reference databases
- ATC codeN05CH01
- Bibliothèque nationale de France ID120121530
- BNCF Thesaurus ID5544
- CAS Registry Number73-31-4
- CCDC Number1210960
- ChEBI ID16796
- ChEMBL IDCHEMBL45
- ChemSpider ID872
- CosIng number35204
- CSD RefcodeMELATN02
- De Agostini IDmelatonina
- Dewey Decimal Classification612.492
- DrugBank IDDB01065
- DrugCentral ID1672
- DSSTOX compound identifierDTXCID002421
- DSSTox substance IDDTXSID1022421
- EC number200-797-7
- ECHA Substance Infocard ID100.000.725
- Encyclopædia Britannica Online IDscience/melatonin
- Encyclopædia Universalis IDmelatonine
- Foundational Model of Anatomy ID74644
- Freebase ID/m/01pxjm
- GND ID4038525-5
- Google Knowledge Graph ID/g/122pl613
- Gran Enciclopèdia Catalana IDmelatonina
- Gran Enciclopèdia Catalana ID (former scheme)0122584
- Great Norwegian Encyclopedia IDmelatonin_-_legemiddel
- Great Russian Encyclopedia portal IDmelatonin-f5f1bb
- Guide to Pharmacology Ligand ID224
- HSDB ID7509
- Human Metabolome Database IDHMDB0001389
- IEV number845-26-044
- InChIInChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
- InChIKeyDRLFMBDRBRZALE-UHFFFAOYSA-N
- J9U entity ID987007563013405171
- KBpedia IDMelatonin
- KEGG IDD08170
- Lex IDmelatonin
- Library of Congress Authorities IDsh85083394
- MassBank accession IDMSBNK-Keio_Univ-KO003432
- MeSH descriptor IDD008550
- MeSH tree codeD03.633.100.473.914.481
- Microsoft Academic ID (discontinued)2778182776
- NALT ID51983
- NDF-RT IDN0000148757
- NDL Authority ID00953147
- NL CR AUT IDph122744
- NSC number56423
- OpenAlex IDC2778182776
- PatientsLikeMe treatment IDmelatonin
- PDB ligand IDML1
- PDB structure ID5I8F
- Probes And Drugs IDPD001629
- PSH ID6289
- PubChem CID896
- Quora topic IDMelatonin
- Reaxys registry number205542
- RxNorm CUI6711
- SPLASHsplash10-0006-0930000000-9e6fcea2c634ac9d85a0
- Store medisinske leksikon IDmelatonin_-_hormon
- SureChEMBL ID19018
- Treccani IDmelatonina
- UK Parliament thesaurus ID457812
- UMLS CUIC0025219
- UniChem compound ID128688
- UNIIJL5DK93RCL
- UNSPSC code12162207
- WikiProjectMed IDMelatonin
- WikiSkripta article ID62716
- WordNet 3.1 Synset ID05418681-n
- Yale LUX IDconcept/6c9d747c-2c50-442a-95a8-80bb013181d9
- YSO ID20075
- Zhihu topic ID19658500