l
lincomycin
Chemical compound
Also known as Frademicina · Lincocin · Cillimycin · U-10149 · Lincomycine · LCM
- Formula
- C₁₈H₃₄N₂O₆S
1
- C₁₈H₃₄N₂O₆S
- Mass
- 406.214 Da
1
- 406.214 Da
Overview
Chemistry
All data
95 statements · 53% with external sources · numbers in brackets are citations
- Canonical SMILES
- CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O
1
- CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O
- Isomeric SMILES
- CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O
- Medical condition treated
- staphylococcal infection
1
- staphylococcal infection(since 1964) approved by: United States Food and Drug Administration
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/BOD072YW0FRetrieved 2018-11-02
- pneumococcal infection(since 1964) approved by: United States Food and Drug Administration
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/BOD072YW0FRetrieved 2018-11-02
- staphylococcal infection
- Active ingredient in
- Lincocin
1
- Lincobac
1
- Lincomed
1
- LINCOCINE 500 mg, capsule
1
Sources- 1.Stated in BDPMbase-donnees-publique.medicaments.gouv.fr/extrait.php?specid=67544048Retrieved 2020-10-26
- Lincocin
- Part of
- lincomycin metabolic process subject has role: participant
1
- lincomycin catabolic process subject has role: reactant
1
- lincomycin biosynthetic process subject has role: product
1
- lincomycin metabolic process subject has role: participant
- Found in taxon
- Streptomyces lincolnensis
23
Sources- 1.Stated in Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466.
- 2.Stated in Biosynthesis of the lincomycins. 2. Studies using stable isotopes on the biosynthesis of methylthiolincosaminide moiety of lincomycin A
- 3.Stated in Isolation and identification of 3-propylidene-.DELTA.1-pyrroline-5-carboxylic acid, a biosynthetic precursor of lincomycin
- 4.Stated in Putative lmbI and lmbH genes form a single lmbIH ORF in Streptomyces lincolnensis type strain ATCC 25466.
- 5.Stated in LmbJ and LmbIH protein levels correlate with lincomycin production in Streptomyces lincolnensis
- 6.Stated in Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production
- Streptomyces albidoflavus
- Streptomyces coelicolor
- Streptomyces lincolnensis
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
On other databases
44 identifiers linking lincomycin across the web's reference databases
- ATC codeJ01FF02
- CAS Registry Number154-21-2
- ChEBI ID6472
- ChEMBL IDCHEMBL1447
- ChemSpider ID2272112
- DeCS ID23297
- DrugBank IDDB01627
- DrugCentral ID1582
- DSSTOX compound identifierDTXCID003215
- DSSTox substance IDDTXSID3023215
- EC number205-824-6
- ECHA Substance Infocard ID100.005.296
- Freebase ID/m/0b707f
- Gran Enciclopèdia Catalana IDlincomicina-0
- Gran Enciclopèdia Catalana ID (former scheme)0119423
- Guide to Pharmacology Ligand ID10941
- HSDB ID3109
- Human Metabolome Database IDHMDB0015564
- InChIInChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
- InChIKeyOJMMVQQUTAEWLP-KIDUDLJLSA-N
- Interlingual Index IDi55707
- KEGG IDC06812
- KNApSAcK IDC00060094
- MassBank accession IDMSBNK-Athens_Univ-AU118001
- MeSH descriptor IDD008034
- MeSH tree codeD03.383.773.532.500
- Microsoft Academic ID (discontinued)2778985905
- Natural Product Atlas IDNPA024602
- NDF-RT IDN0000147891
- OpenAlex IDC2778985905
- PDB ligand ID3QB
- PDB structure ID4WH5
- Probes And Drugs IDPD013336
- PubChem CID3000540
- Reaxys registry number707677
- Römpp online IDRD-12-01191
- RxNorm CUI6398
- SPLASHsplash10-004i-0900000000-70466cfb7e0692d073a0
- SureChEMBL ID4010
- UMLS CUIC0023726
- UniChem compound ID264690
- UNIIBOD072YW0F
- WikiProjectMed IDLincomycin
- WordNet 3.1 Synset ID03675948-n