f
fosfomycin
Chemical compound
Also known as Phosphonemycin · Fosfomycinum · Phosphonomycin · 1R-cis-(1,2-Epoxypropyl)phosphonic acid · FCM · (1R,2S)-Epoxypropylphosphonic acid
- Formula
- C₃H₇O₄P
1
- C₃H₇O₄P
- Mass
- 138.008 Da
1
- 138.008 Da
Overview
Chemistry
All data
79 statements · 71% with external sources · numbers in brackets are citations
- Medical condition treated
- Escherichia coli infectious disease
1
- urinary tract infection
2
Sources- 1.Stated in NDF-RTRetrieved 2016-12-13
- 2.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- cystitis
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- Escherichia coli infectious disease
- Canonical SMILES
- CC1C(O1)P(=O)(O)O
1
- CC1C(O1)P(=O)(O)O
- Isomeric SMILES
- C[C@H]1[C@H](O1)P(=O)(O)O
1
- C[C@H]1[C@H](O1)P(=O)(O)O
- Found in taxon
- Pseudomonas viridiflava
- Pseudomonas syringae
- Streptomyces wedmorensis
9
Sources- 1.Stated in Studies on the biosynthesis of fosfomycin. 2. Conversion of 2-hydoxypropylphosphonic acid to fosfomycin by blocked mutants of Streptomyces wedmorensis
- 2.Stated in Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin
- 3.Stated in Studies on the biosynthesis of fosfomycin. 3. Detection of phosphoenol-pyruvate phosphomutase activity in a fosfomycin high-producing strain of Streptomyces wedmorensis and characterization of its blocked mutant NP-7
- 4.Stated in Studies on the biosynthesis of fosfomycin. Conversion of 2-hydroxyethylphosphonic acid and 2-aminoethylphosphonic acid to fosfomycin.
- 5.Stated in Cloning and nucleotide sequence of fosfomycin biosynthetic genes of Streptomyces wedmorensis
- 6.Stated in Initiating a crystallographic analysis of recombinant (S)-2-hydroxypropylphosphonic acid epoxidase from Streptomyces wedmorensis
- Streptomyces fradiae
5
Sources- 1.Stated in Incorporation ofL-[Methyl-2H3]methionine and 2-[Hydroxy-18O]hydroxyethylphosphonic Acid into Fosfomycin inStreptomyces fradiae—An Unusual Methyl Transfer
- 2.Stated in Biosynthesis of natural products with a P–C bond. Part 8: on the origin of the oxirane oxygen atom of fosfomycin in Streptomyces fradiae
- 3.Stated in Phosphonomycin, a New Antibiotic Produced by Strains of Streptomyces
- 4.Stated in Biosynthesis of fosfomycin by Streptomyces fradiae
- 5.Stated in Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase
- Arabidopsis thaliana
- Streptomyces
- LiverTox likelihood score
- LiverTox toxicity likelihood category D
1
Sources- 1.Stated in LiverToxncbi.nlm.nih.gov/books/n/livertox/FosfomycinRetrieved 2021-04-08
- LiverTox toxicity likelihood category D
On other databases
43 identifiers linking fosfomycin across the web's reference databases
- ATC codeJ01XX01
- CAB ID33186
- CAS Registry Number23155-02-4
- ChEBI ID28915
- ChEMBL IDCHEMBL1757
- ChemSpider ID394204
- DrugBank IDDB00828
- DrugCentral ID1243
- DSSTOX compound identifierDTXCID0028454
- DSSTox substance IDDTXSID4048480
- EC number245-463-1
- ECHA Substance Infocard ID100.041.315
- Electronic Essential Medicines List medicine ID343
- Freebase ID/m/02w__4_
- Guide to Pharmacology Ligand ID10813
- Human Metabolome Database IDHMDB0014966
- InChIInChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1
- InChIKeyYMDXZJFXQJVXBF-STHAYSLISA-N
- KEGG IDD04253
- KNApSAcK IDC00000789
- LiverTox IDFosfomycin
- MedlinePlus drug identifiera697008
- MeSH concept IDM0008779
- MeSH descriptor IDD005578
- MeSH tree codeD02.705.429.625
- Microsoft Academic ID (discontinued)2778897966
- Natural Product Atlas IDNPA024868
- NDF-RT IDN0000022052
- OpenAlex IDC2778897966
- PatientsLikeMe treatment IDfosfomycin
- PDB ligand IDFCN
- PDB structure ID1LQP
- Probes And Drugs IDPD009701
- PubChem CID446987
- Quora topic IDFCM
- Reaxys registry number1680831
- RxNorm CUI4550
- SPLASHsplash10-03di-2980000000-005d5b96a1e9219362d0
- SureChEMBL ID50951
- UMLS CUIC0016610
- UniChem compound ID41156
- UNII2N81MY12TE
- WikiProjectMed IDFosfomycin