f
flutamide
Chemical compound
Also known as alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide · 4'-nitro-3'-trifluoromethylisobutyranilide · FTA · NFBA · niftolide
- Formula
- C₁₁H₁₁F₃N₂O₃
1
- C₁₁H₁₁F₃N₂O₃
- Mass
- 276.0722 Da
1
- 276.0722 Da
Overview
Chemistry
All data
65 statements · 57% with external sources · numbers in brackets are citations
- Medical condition treated
- prostate cancer
1
- prostate carcinoma(since 1989) approved by: United States Food and Drug Administration
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/76W6J0943ERetrieved 2018-11-02
- prostate cancer
- Canonical SMILES
- CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
1
- CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
- Defined daily dose
- 0.75 g route of administration: oral administration
- Subject has role
- antiandrogen
1
- hormonal antineoplastic agent
1
- developmental toxicant(since 1990)
1
Sources- 1.Stated in California Proposition 65 list of chemicalsoehha.ca.gov/chemicals/flutamideRetrieved 2020-02-26
- antiandrogen
- MCN code
- 2924.29.62
- Physically interacts with
- androgen receptor subject has role: antagonist
1
- androgen receptor subject has role: antagonist
- LiverTox likelihood score
- LiverTox toxicity likelihood category A
1
Sources- 1.Stated in LiverToxncbi.nlm.nih.gov/books/n/livertox/FlutamideRetrieved 2021-04-08
- LiverTox toxicity likelihood category A
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
On other databases
41 identifiers linking flutamide across the web's reference databases
- ATC codeL02BB01
- CA PROP 65 IDflutamide
- CAS Registry Number13311-84-7
- ChEBI ID5132
- ChEMBL IDCHEMBL806
- ChemSpider ID3280
- DrugBank IDDB00499
- DrugCentral ID1223
- DSSTOX compound identifierDTXCID9011121
- DSSTox substance IDDTXSID7032004
- EC number236-341-9
- ECHA Substance Infocard ID100.033.024
- Freebase ID/m/094rnd
- Guide to Pharmacology Ligand ID6943
- Human Metabolome Database IDHMDB0014642
- InChIInChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
- InChIKeyMKXKFYHWDHIYRV-UHFFFAOYSA-N
- J9U entity ID987007536794705171
- KEGG IDC07653
- Library of Congress Authorities IDsh91005137
- LiverTox IDFlutamide
- MassBank accession IDSM856754
- MedlinePlus drug identifiera697045
- MeSH concept IDM0008651
- MeSH descriptor IDD005485
- MeSH tree codeD02.065.199.420
- Microsoft Academic ID (discontinued)2778313021
- NDF-RT IDN0000147534
- NSC number147834
- OpenAlex IDC2778313021
- PatientsLikeMe treatment IDflutamide
- Probes And Drugs IDPD001517
- PubChem CID3397
- Reaxys registry number2157663
- RxNorm CUI4508
- SPLASHsplash10-004i-0090000000-983edf51e9c479db69a5
- SureChEMBL ID3934
- UMLS CUIC0016384
- UniChem compound ID466998
- UNII76W6J0943E
- WikiProjectMed IDFlutamide