e
- Formula
- C₂₄H₂₁F₂NO₃
1
- C₂₄H₂₁F₂NO₃
- Mass
- 409.149 Da
1
- 409.149 Da
Overview
Chemistry
All data
67 statements · 60% with external sources · numbers in brackets are citations
- Isomeric SMILES
- C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
1
- C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
- Canonical SMILES
- C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
1
- C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
- Defined daily dose
- 10 milligram route of administration: oral administration
- Physically interacts with
- NPC1 like intracellular cholesterol transporter 1 subject has role: antagonist
1
- NPC1 like intracellular cholesterol transporter 1 subject has role: antagonist
- LiverTox likelihood score
- LiverTox toxicity likelihood category C
1
Sources- 1.Stated in LiverToxncbi.nlm.nih.gov/books/n/livertox/EzetimibeRetrieved 2021-04-08
- LiverTox toxicity likelihood category C
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
- Significant drug interaction
- fenofibrate side effect: gallstone disease
- Medical condition treated
- familial hypercholesterolemia
1
- familial hypercholesterolemia(since 2002) approved by: United States Food and Drug Administration · applies to jurisdiction: United States
1
Sources- 1.Stated in Inxight: Drugs Databasedrugs.ncats.io/drug/EOR26LQQ24Retrieved 2018-11-02
- lipedema
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- rare dyslipidemia
1
Sources- 1.Stated in Drug Indications Extracted from FAERSRetrieved 2018-10-02
- familial hypercholesterolemia
On other databases
44 identifiers linking ezetimibe across the web's reference databases
- ATC codeC10AX09
- CAS Registry Number163222-33-1
- ChEBI ID49040
- ChEMBL IDCHEMBL1138
- ChemSpider ID132493
- DeCS ID55913
- DrugBank IDDB00973
- DrugCentral ID1125
- DSSTOX compound identifierDTXCID9024223
- DSSTox substance IDDTXSID1044223
- EC number682-606-0
- ECHA Substance Infocard ID100.207.996
- Freebase ID/m/03jkvr
- Guide to Pharmacology Ligand ID6816
- HSDB ID7737
- Human Metabolome Database IDHMDB0015108
- InChIInChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
- InChIKeyOLNTVTPDXPETLC-XPWALMASSA-N
- KEGG IDD01966
- LiverTox IDEzetimibe
- MedlinePlus drug identifiera603015
- MeSH concept IDM0422151
- MeSH descriptor IDD000069438
- MeSH tree codeD03.383.082.301.550
- Microsoft Academic ID (discontinued)2778657065
- NDF-RT IDN0000148785
- NSC number758923
- OpenAlex IDC2778657065
- PatientsLikeMe treatment IDezetimibe
- PDB ligand IDH56
- Probes And Drugs IDPD002999
- PubChem CID150311
- Reaxys registry number7981967
- RxNorm CUI341248
- SPLASHsplash10-00di-0090000000-2095f1a903775ffc154f
- SureChEMBL ID2871
- UK Parliament thesaurus ID529338
- UMLS CUIC1142985
- UniChem compound ID344973
- UNIIEOR26LQQ24
- UNSPSC code51121819
- WikiProjectMed IDEzetimibe
- WikiSkripta article ID35393
- World Health Organisation international non-proprietary name numeric ID8010