Danforth is a surname. Notable people with the surname include:Asa Danforth (1746–1818), American highway engineer of the Revolutionary War era
Asa Danforth Jr. (1768–1821), Upper Canada highway engineer
Charles Haskell Danforth (1833–1969), American comparative anatomist
Dave Danforth (1890–1970), American professional baseball player
Elizabeth Danforth, creator in the role-playing game and video game industry
Elliott Danforth, New York State Treasurer 1890–1893
Emily M. Danforth, US author
George F. Danforth (1819–1899), New York judge
Harold Warren Danforth (1916–1993), Member of the Parliament of Canada
John Danforth, 27th United States Ambassador to the United Nations
Justin Danforth, professional ice hockey player
Loring Danforth, anthropology professor at Bates College in Lewiston, Maine
Samuel Danforth (1626–1674), Puritan minister
Stuart Taylor Danforth (1900–1938), American professor of zoology in Puerto Rico
Thomas Danforth (1622–1699), a judge in the Salem witch trials
Walter R. Danforth (1787–1861), journalist and 4th mayor of Providence, Rhode Island.
William H. Danforth (1870–1955), founder of Ralston-Purina
William Henry Danforth, M.D. (1926–2020), American physician and educator