d
danazol
Chemical compound
Also known as Danocrine® · Danazol · Cyclomen · Danazolum
- Formula
- C₂₂H₂₇NO₂
1
- C₂₂H₂₇NO₂
- Mass
- 337.2042 Da
1
- 337.2042 Da
Overview
Chemistry
All data
102 statements · 56% with external sources · numbers in brackets are citations
- Isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5
1
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5
- Canonical SMILES
- CC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=C(CC34C)C=NO5
1
- CC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=C(CC34C)C=NO5
- Defined daily dose
- 0.6 g route of administration: oral administration
- Subject has role
- estrogen antagonist
1
- developmental toxicant(since 1990)
1
Sources- 1.Stated in California Proposition 65 list of chemicalsoehha.ca.gov/chemicals/danazolRetrieved 2020-02-24
- estrogen antagonist
- Legal status (medicine)
- boxed warning
1
Sources- 1.“FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.”nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- boxed warning
- Significant drug interaction
- simvastatin side effect: rhabdomyolysis
- simvastatin side effect: muscular disease
- rac-warfarin side effect: retroperitoneal hemorrhage
- cyclosporine side effect: kidney failure
- cyclosporine side effect: cholestasis
- cyclosporine side effect: paresthesia
- carbamazepin side effect: seizure
- carbamazepin side effect: nystagmus
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- carbamazepin side effect: ataxia
- carbamazepin side effect: monocular diplopia
- carbamazepin side effect: headache disorder
- carbamazepin side effect: vomiting
- carbamazepin side effect: apnea
- carbamazepin side effect: coma
On other databases
47 identifiers linking danazol across the web's reference databases
- ATC codeG03XA01
- CA PROP 65 IDdanazol
- CAS Registry Number17230-88-5
- ChEBI ID4315
- ChEMBL IDCHEMBL1479
- ChemSpider ID26436
- DrugBank IDDB01406
- DrugCentral ID779
- DSSTOX compound identifierDTXCID202880
- DSSTox substance IDDTXSID2022880
- EC number241-270-1
- ECHA Substance Infocard ID100.037.503
- Freebase ID/m/0982_t
- Guide to Pharmacology Ligand ID6942
- Human Metabolome Database IDHMDB0002835
- IATE entry ID38533
- InChIInChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1
- InChIKeyPOZRVZJJTULAOH-LHZXLZLDSA-N
- KEGG IDD00289
- MassBank accession IDMSBNK-LCSB-LU025301
- MedlinePlus drug identifiera682599
- MeSH descriptor IDD003613
- MeSH tree codeD04.210.500.745.432.235
- Microsoft Academic ID (discontinued)2777416354
- National Drug Code42291-243
- National Library of Spain SpMaBN IDXX533130
- NCI Dictionary of Cancer Terms entrydanazol
- NDF-RT IDN0000146564
- NE.se IDdanazol
- NSC number270916
- OpenAlex IDC2777416354
- Oxford Reference overview ID20110803095659206
- PatientsLikeMe treatment IDdanazol
- PDB ligand IDQA1
- Probes And Drugs IDPD003037
- PubChem CID28417
- Reaxys registry number4851114
- Römpp online IDRD-04-00084
- RxNorm CUI3102
- ScienceDirect topic IDagricultural-and-biological-sciences/danazol
- SPLASHsplash10-000i-0009000000-9e745b8feecd354f6618
- SureChEMBL ID21107
- UMLS CUIC0010961
- UniChem compound ID219490
- UNIIN29QWW3BUO
- UNSPSC code51181902
- WikiProjectMed IDDanazol