curcumin
Chemical compound, main yellow-orange-colored pigment and active principle of turmeric or curcuma
Also known as Terra merita · Yo-kin · Gelbwurz · C.I. 75300 · Yellow puccoon · Safran D'inde
- Formula
- C₂₁H₂₀O₆
1
- C₂₁H₂₀O₆
- Mass
- 368.126 Da
1
- 368.126 Da
- Melting point
- 173°C
1
- 173°C
Overview
Chemistry
All data
123 statements · 60% with external sources · numbers in brackets are citations
- Isomeric SMILES
- COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O
1
- COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O
- Canonical SMILES
- COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
1
- COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
- Physically interacts with
- E1A binding protein p300 subject has role: enzyme inhibitor
1
- E1A binding protein p300 subject has role: enzyme inhibitor
- Part of
- response to curcumin subject has role: reactant
1
- cellular response to curcumin subject has role: reactant
1
- curcumin metabolic process subject has role: participant
1
- curcumin catabolic process subject has role: reactant
1
- curcumin synthase activity
1
- response to curcumin subject has role: reactant
- Has use
- food coloring
- dye
1
- food additive
- nootropic
1
Sources- 1.“Which Trendy Brain-Boosting Supplements Might Actually Work”menshealth.com/health/a66104054/brain-boosting-supplementsRetrieved 2025-09-26
- Found in taxon
- Curcuma longa
55
Sources- 1.Stated in Thin-layer chromatographic determination of curcumine (turmeric) in spices
- 2.Stated in SIMULTANEOUS DETERMINATION OF CURCUMINOIDS IN CURCUMA SAMPLES USING HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY
- 3.Stated in Biological activities of Curcuma longa L.
- 4.Stated in Turmeric (Curcuma longa): Effects of Curcuma longa Extracts Compared With Ibuprofen for Reduction of Pain and Functional Improvement in Patients With Knee Osteoarthritis
- 5.Stated in Chapter 5. A Most Precious Gift
- 6.Stated in Curcumin inhibits ACTH- and angiotensin II-stimulated cortisol secretion and Ca(v)3.2 current
- Curcuma amada
- Curcuma aeruginosa
2
Sources- 1.Stated in Curcumin, an Active Constiuent of the Ancient Medicinal Herb Curcuma longa L.: Some Uses and the Establishment and Biological Basis of Medical Efficacy
- 2.Stated in Antioxidant activity of tropical ginger extracts and analysis of the contained curcuminoids
- Curcuma xanthorrhiza
8
Sources- 1.Stated in Curcumin, an Active Constiuent of the Ancient Medicinal Herb Curcuma longa L.: Some Uses and the Establishment and Biological Basis of Medical Efficacy
- 2.Stated in Antioxidative curcuminoids from rhizomes of Curcuma xanthorrhiza
- 3.Stated in Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation.
- 4.Stated in Antioxidant activity of tropical ginger extracts and analysis of the contained curcuminoids
- 5.Stated in Diarylheptanoids from the rhizomes of Curcuma xanthorrhiza and Alpinia officinarum.
- 6.Stated in Terpenoids and Curcuminoids of the Rhizoma of Curcuma xanthorrhiza ROXB
- Curcuma zedoaria
3
Sources- 1.Stated in Curcumin, an Active Constiuent of the Ancient Medicinal Herb Curcuma longa L.: Some Uses and the Establishment and Biological Basis of Medical Efficacy
- 2.Stated in Hepatoprotective constituents from zedoariae rhizoma: absolute stereostructures of three new carabrane-type sesquiterpenes, curcumenolactones A, B, and C.
- 3.Stated in Medicinal foodstuffs. XXVIII. Inhibitors of nitric oxide production and new sesquiterpenes, zedoarofuran, 4-epicurcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, from Zedoariae Rhizoma
- Curcuma chuanyujin
- Curcuma mangga
- Alpinia galanga
Show 21 moreShow less
- Amomum compactum
- ginger
1
- Zingiber zerumbet
- Zingiber spectabile
- Murraya koenigii
1
- Morella rubra
- Myrica rubra
- Curcuma kwangsiensis
- Zingiber cassumunar
- Wurfbainia compacta
- Zingiber purpureum
- liquorice
- Podosordaria nigripes
- Maclura tricuspidata
- Aspergillus versicolor
- Glycyrrhiza inflata
- Strychnos angustiflora
- Zingiber montanum
- Colletotrichum gloeosporioides
- Zingiberaceae
- Chondrostereum
- Curcuma longa
- Median lethal dose (LD50)
- 1,500 milligram per kilogram applies to taxon: house mouse · route of administration: intraperitoneal injection
On other databases
46 identifiers linking curcumin across the web's reference databases
- BabelNet ID02571772n
- CAB ID121178
- CAMEO Chemicals ID20062
- CAS Registry Number458-37-7
- ChEBI ID3962
- ChEMBL IDCHEMBL140
- ChemSpider ID839564
- Colour Index International constitution ID75300
- CosIng number55538
- DeCS ID3495
- DrugBank IDDB11672
- DSSTOX compound identifierDTXCID901421
- DSSTox substance IDDTXSID8031077
- E numberE100
- EC number207-280-5
- ECHA Substance Infocard ID100.006.619
- Freebase ID/m/01vlkr
- Great Norwegian Encyclopedia IDkurkumin_-_E100
- Guide to Pharmacology Ligand ID7000
- HSDB ID4334
- Human Metabolome Database IDHMDB0002269
- InChIInChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
- InChIKeyVFLDPWHFBUODDF-FCXRPNKRSA-N
- International Numbering System number100(i)
- KEGG IDC10443
- Lex IDcurcumin
- MassBank accession IDMSBNK-Fac_Eng_Univ_Tokyo-JP001420
- MeSH descriptor IDD003474
- MeSH tree codeD02.455.326.146.485.222.222
- Microsoft Academic ID (discontinued)2778250585
- NALT ID30815
- Nikkaji IDJ5.762B
- NSC number32982
- Open Food Facts food additive IDe100-curcumin
- OpenAlex IDC2778250585
- PDB ligand IDCC9
- Probes And Drugs IDPD011359
- PubChem CID969516
- Reaxys registry number2306965
- RTECS numberMI5230000
- RxNorm CUI2955
- SPLASHsplash10-014i-0009200000-3e33efd2452a1862bc12
- SureChEMBL ID8440
- UMLS CUIC0010467
- UniChem compound ID896764
- UNIIIT942ZTH98