Berthold is a German surname. Notable people with the name include:Arnold Adolph Berthold (1803–1861), German physiologist and zoologist
Avgust Berthold (1880–1919), Slovene photographer
Barbara Metselaar Berthold (1951–2024), German photographer and filmmaker
Daniel Berthold, American philosopher
David Berthold, Australian theatre director
Fred Berthold (1922–2019), American theologian and academic
Frederic Berthold, Austrian World Cup alpine ski racer
Gerhard Berthold (1891–1942), German general
Helmut Berthold (1911–2000), German handball player
Hermann Berthold (1831–1904), Prussian and German printer
Hermine Berthold (1896–1990), German resistance member and politician
Kate McKinnon Berthold, American actress and comedian
Lothar Berthold (1926–2007), German politician, historian and publisher
Luc Berthold, Canadian politician
Mathias Berthold, Austrian alpine skier
Michael Berthold, German computer scientist
Richard Berthold, American historian of ancient Greece
Rudolf Berthold (1891–1920), German WWI flying ace
Rudolf Berthold (footballer) (1903–1976), German footballer
Simón Berthold, Mexican anarchist militant
Thomas Berthold, German footballer and soccer coach